The two adults from the 4WD – Mel Martin, 33, and Dylan Wadley, 23 – remain in the Princess Alexandra Hospital. Their injuries are not considered to be life-threatening.
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However, 13-year-old Leo and four-year-old Mia could not be saved, despite extensive resuscitation efforts at the scene by witnesses and paramedics.
Motorcyclist Mark Green, who stopped to help, said Mr Wadley, who was injured, tried to save his children.
“The father of the children was screaming in the water that his kids were in the car,” he said.
“I think the dad had a broken leg but he was trying to get the door [open] but it was jammed.”
Police Inspector Douglas McDonald said they were all wearing seatbelts and alcohol was not a contributing factor.
However, fatigue was a factor that would be investigated.
A report will be prepared for the coroner.